Figure 5.

Effects of Endothelium‐specific CYP2J2 overexpression on macrophages polarization in eWAT of old mice. (a) M1 marker genes of macrophages CD11c and iNOS and (b) M2 marker genes of macrophages Arg1 and Chi3 l3 were measured by real‐time PCR. (c‐e) Representative immunoblots and quantitation of M1 (CD11c and iNOS) and M2 (Arg1 and Chi3 l3) markers. Data are shown as means ± SE (n = 8 per genotype). ^§ p < .05,16 mWT vs. 3 mWT; ^§§ p < .01, 16 mWT vs. 3 mWT; ^# p < .05, 16 m2J2‐Tr vs. 16 mWT; ^## p < .01, 16 m2J2‐Tr vs. 16 mWT