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. 2018 Feb 8;3:11. doi: 10.21037/tgh.2018.01.07

Figure 2.

Figure 2

The algorithm of pathological diagnosis of GIST. &, CD34 is not specific for GIST; #, others include leiomyoma & leiomyosarcoma (desmin-positive), schwannoma (S-100-positive), solitary fibrous tumor (CD34-positive and nuclear STAT6-positive), desmoid (nuclear beta-catenin-positive), inflammatory myofibroblastic tumor (ALK-positive), PEComa (HMB45-positive) and others; $, others include PEComa (HMB45-positive), glomus tumor (smooth muscle actin-positive & vimentin-positive), solitary fibrous tumor (CD34-positive and nuclear STAT6-positive), malignant melanoma (S-100 positive, HMB45-positive), neuroendocrine tumor (several biomarkers), and others. GIST, gastrointestinal stromal tumor.