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PZH decreased the levels of IL-23, IL-17A, CCL3, and CCL5 in the CNS of EAE rats. Representative immunohistochemistry images (left) and IOD means (right) of IL-23 (a), IL-17A (b), CCL3 (c), and CCL5 (d) in the spinal cord of rats from each group. Original magnification 200x. All data were shown as the mean ± SD. ∗P < 0.05 and ∗∗P < 0.01.
