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. Author manuscript; available in PMC: 2018 Mar 13.
Published in final edited form as: Biochemistry. 2017 Jan 9;56(3):525–533. doi: 10.1021/acs.biochem.6b00945

Table 2.

Activity of LPL variants on lipoproteins isolated from human blood

Parameter Vmax (chylomicrons)
TG (M/s)
Km (chylomicrons)
(M)
rate (VLDL)
FFA (M/s/mol lipase)
LPL (5.32 ± 1.37) × 10−4 (6.09 ± 2.82) × 10−3 (4.56 ± 1.45) × 104
LPLS447X (4.83 ± 0.9) × 10−4 (4.74 ± 1.68) × 10−3 (5.80 ± 1.10) × 104