. 2017 Mar 25;65(2):268–275. doi: 10.1093/cid/cix277

Table 3.

Clinical Outcomes Among Singleton Infants in the Congenital Chagas Disease Cohort Study, Santa Cruz and Camiri, Bolivia

Characteristic	M + B + Infected Mother–Infected Infant (N = 32)^a	M + B − Infected Mother–Uninfected Infant (N = 252)^b	M − B − Uninfected Mother–Uninfected Infant (N = 1360)^c	M + B + vs M + B –	P Value	M + B – vs M – B –
Characteristic	M + B + Infected Mother–Infected Infant (N = 32)^a	M + B − Infected Mother–Uninfected Infant (N = 252)^b	M − B − Uninfected Mother–Uninfected Infant (N = 1360)^c	M + B + vs M + B –	M + B + vs M – B –	M + B – vs M – B –
Maternal characteristic
Primiparous	7 (21.9)	48 (19.7)	494 (36.3)	NS	NS	<0.001
Maternal age (median [IQR])	23.5 [19.6, 28.1]	26.9 [22.0, 34.2]	22.7 [19.0, 28.9]	<0.01	NS	<0.001
Cesarean section	19 (59.4)	121 (49.6)	613 (45.1)	NS	NS	NS
Premature rupture of membranes	4 (12.5)	16 (6.7)	196 (14.8)	NS	NS	<0.001
Infant characteristic
Female sex	26 (68.4)	114 (46.7)	658 (48.5)	<0.05	NS	NS
Birth weight (median [IQR])	2980 [2500, 3525]	3300 [3070, 3650]	3300 [2960, 3600]	<0.05	<.05	NS
Birth weight <2500 g	7 (21.9)	12 (5.0)	107 (7.9)	<0.01	<.05	NS
1-minute Apgar score <7	1 (3.1)	11 (4.5)	41 (3.0)	NS	NS	NS
5-minute Apgar score <7	0 (0)	1 (0.4)	4 (0.3)	NS	NS	NS
Premature by exam	6 (18.8)	11 (4.6)	90 (6.6)	<0.01	<.05	NS
Hospitalized at birth	5 (15.6)	16 (6.7)	131 (9.7)	NS	NS	NS
Respiratory distress	4 (12.5)	10 (4.2)	119 (8.8)	0.07	NS	<0.05

Abbreviations: IQR, interquartile range; NS, nonsignificant.

^aExcludes 3 sets of twins, all concordantly infected.

^bExcludes 4 sets of twins, 174 infants with no specimen at 6 or 9 months, and 23 infants whose final serology was inconclusive.

^cExcludes 15 sets of twins.