Table 1.
Baseline Characteristics of Study Cohort From the Cystic Fibrosis Foundation Patient Registry (2003)
| Characteristic | <18 y (n = 12702) |
≥18 y (n = 8320) |
All Subjects (N = 21022) |
|---|---|---|---|
| Female sex | 6217 (49) | 3908 (47) | 10125 (48) |
| Age at CF diagnosis, y, mean (SD) | 1.4 (2.6) | 5.9 (10.4) | 3.2 (7.2) |
| Age group at CF diagnosis | |||
| 0–3 y | 10853 (85) | 5451 (66) | 16304 (78) |
| >3–5 y | 802 (6) | 577 (7) | 1379 (7) |
| >5 y | 1047 (8) | 2292 (28) | 3339 (16) |
| Age at year end (2003), y, mean (SD) | 9.5 (5.0) | 28.7 (9.4) | 17.1 (11.8) |
| Age group at year end (2003) | |||
| <6 y | 3652 (29) | 0 | 3652 (17) |
| ≥6–12 y | 4506 (35) | 0 | 4506 (21) |
| ≥12–18 y | 4544 (36) | 0 | 4544 (22) |
| ≥18–36 y | 0 | 6614 (79) | 6614 (31) |
| ≥36 y | 0 | 1706 (21) | 1706 (8) |
| Genotype | |||
| Other/unknown | 2248 (18) | 1933 (23) | 4181 (20) |
| Delta F508 heterozygous | 4296 (34) | 2934 (35) | 7230 (34) |
| Delta F508 homozygous | 6158 (48) | 3453 (42) | 9611 (45) |
| Race | |||
| White, non-Hispanic | 11164 (88) | 7775 (93) | 18939 (90) |
| Black, non-Hispanic | 559 (4) | 211 (3) | 770 (4) |
| Other/unknown | 979 (8) | 334 (4) | 1313 (6) |
| Infection status | |||
| Pseudomonas aeruginosa present | 6143 (48) | 6806 (82) | 12949 (62) |
| Burkholderia complex present | 254 (2) | 333 (4) | 587 (3) |
| Staphylococcus aureus present | 7748 (61) | 3494 (42) | 11242 (53) |
| FEV1% predicted | |||
| No. | 8520 | 7392 | 15912 |
| Mean (SD) | 86 (21) | 60 (24) | 74 (26) |
| FEV1, L | |||
| No. | 8520 | 7394 | 15914 |
| Mean (SD) | 1.9 (0.8) | 2.3 (1.0) | 2.1 (0.9) |
| Insurance status | |||
| Private/HMO | 7966 (63) | 5507 (66) | 13473 (64) |
| Public | 4379 (34) | 2406 (29) | 6785 (32) |
| Other/unknown | 40 (0) | 59 (1) | 99 (0) |
| No insurance | 317 (2) | 348 (4) | 665 (3) |
| Median zip code income (IQR) | $42083 | $43077 | $42659 |
Data are presented as No. (%) unless otherwise indicated.
Abbreviations: CF, cystic fibrosis; FEV1, forced expiratory volume in 1 second; HMO, health maintenance organization; IQR, interquartile range; SD, standard deviation.