Skip to main content
. 2017 May 18;65(1):150–153. doi: 10.1093/cid/cix245

Table 1.

Patient Characteristics, Laboratory Parameters, and Xenodiagnosis Results From 3 Patients With Post–Kala-azar Dermal Leishmaniasis, Bangladesh

Characteristic or Finding Patient 1 Patient 2 Patient 3
Sex Male Male Male
Age, y 24 40 35
Profession Tailor Business Construction
History of VL No Yes Yes
VL treatment drug NA SSG SSG
Time since VL treatment, mo NA 180 120
Previous PKDL treatment Yes No Yes
 PKDL treatment drug AmBisome NA SSG
 Date of PKDL treatment April 2014 NA July 2006
Duration of current lesions, mo 7 174 108
Rash type
 Macular Minor No Extensive
 Papular Minor No No
 Nodular No Abundant No
Score for extent of rash 2 62 558
DAT titer 12 800 12 800 12 800
rK39 Positive Positive Positive
Buffy coat qPCR Negative Negative Negative
Skin biopsy results
 Microscopy Positive 1+ Positive 1+ Positive 1+
 Cycle thresholda 25 30 22
 Parasites per micrograma 21 621 1428 63 058
Xenodiagnosis results, no./No. (%)
Hand in cage of sand flies
 Fed/exposed flies 2/11 (18.2) 4/15 (26.7) 6/13 (46.2)
 Microscopy positive/dissected flies 0/2 (0) 0/4 (0) 0/4 (0)
 PCR positive/processed flies 0/2 (0) 2/4 (50) 3/6 (50)
 Tube of sand flies applied to skin
 Fed/exposed flies 1/7 (14.3) 7/12 (58.3) 2/9 (22.2)
 Microscopy positive/dissected flies 1/1 (100) 0/5 (0) 0/0 (0)
 PCR positive/processed flies Not done 1/7 (14.2) 0/2 (0)
 Positive by any method 1/5 (20) 3/20 (15) 3/12 (25)

Abbreviations: DAT, direct agglutination test; NA, not applicable; qPCR, quantitative polymerase chain reaction; PKDL, post–kala-azar dermal leishmaniasis; SSG, sodium stibogluconate; VL, visceral leishmaniasis.

aMean of 2 assays by qPCR.