Table 1. Demographic and optical coherence tomography angiography features.
| Features | Affected male CHM patients, N=9 patients, 17 eyes | Female CHM carriers, N=5 patients, 9 eyes | Age-matched controls, N=14 patients, 28 eyes | P-value |
|---|---|---|---|---|
| Age years (range) | 33.44±14.44 (12 to 57) | 45.90±16.90 (21 to 64) | 38.74±14.08 (12 to 60) | 0.33 |
| BCVA LogMAR (range) | 0.47±0.31 (0.00 to 3.00) | −0.08±0.00 (0.04 to 0.00) | 0.03±0.00 (−0.08 to 0.03) | <0.01a |
| Refraction spherical equivalent (range) | −1.00±1.90 (−5.00 to 0.75) | 0.20±0.40 (0.00 to 1.00) | −0.60±1.20 (−4.00 to 0.00) | 0.69 |
| SRVN area with flow mm2 (range) | 12.93±2.06 (9.11 to 15.56) | 15.36±0.60 (14.62 to 16.00) | 15.30±1.35 (11.69 to 17.55) | <0.01a |
| CC area with flow mm2 (range) | 6.97±5.26 (0.20 to 13.91) | 21.65±0.17 (21.38 to 21.85) | 21.36±0.76 (19.65 to 22.59) | 0.00a |
| Superficial FAZ mm2 (range) | 0.60±0.89 (0.16 to 2.93) | 0.31±0.57 (0.26 to 0.39) | 0.27±0.10 (0.11 to 0.48) | 0.59 |
Abbreviations: BCVA, best corrected visual acuity; CC, choriocapillaris; FAZ, foveal avascular zone; SRVN, superficial retinal vessel network.
Values are reported as mean±SD.
ANOVA test for the age distribution, Kruskal–Wallis test for BCVA, refraction, SRVN, CC, and superficial FAZ.
a
Statistical significance.