Figure 3.

Plasma indoleamine 2, 3-dioxygenase (IDO) activity human immunodeficiency virus (HIV)–infected controls (n = 70), HIV-infected patients with pneumonia (n = 37), and HIV-infected patients with active tuberculosis (n = 32). Patients with active tuberculosis had significantly higher IDO values than patients with pneumonia. At a cutoff of 0.80, IDO activity classified all but 4 pneumonia cases as “not tuberculosis.” The red dot indicates a patient in whom pneumonia was first diagnosed and who later progressed to active tuberculosis disease within 6 months. Medians and interquartile ranges are shown. P values were determined using Kruskal-Wallis tests with Dunn posttests.