Table 1.
Characteristics of Patients Who Developed Incident Colonization or Infection With Mycobacterium abscessus During or up to 30 Days After Hospitalization, 2013–2015
| Characteristic | Overall (January 2013– December 2015) (n = 126) |
Phase 1 (August 2013– May 2014) (n = 71) |
Phase 2 (December 2014– June 2015) (n = 24) |
|||
|---|---|---|---|---|---|---|
| Median age, y (IQR) | 63 (50–68) | 63 (50–67) | 59 (49–68) | |||
| Male sex, No. (%) | 92 (73) | 52 (73) | 15 (63) | |||
| Patient type, No. (%) | ||||||
| Lung transplant | 58 (46) | 39 (55) | 5 (21) | |||
| Cardiac surgery | 27 (21) | 9 (13) | 13 (54) | |||
| VAD (no heart transplant) | 9 (7) | 2 (3) | 6 (25) | |||
| Heart transplant | 8 (6) | 4 (6) | 4 (17) | |||
| Valve surgery (no VAD) | 6 (5) | 2 (3) | 2 (8) | |||
| Coronary artery bypass grafting (no valve surgery) | 3 (2) | 1 (1) | 1 (4) | |||
| Ventricular septal defect repair | 1 (1) | 0 (0) | 0 (0) | |||
| Malignancy (no hematopoietic stem cell transplant) | 10 (8) | 5 (7) | 1 (4) | |||
| Chronic lung disease (no lung transplant) | 8 (6) | 4 (6) | 2 (8) | |||
| Hematopoietic stem cell transplant | 5 (4) | 5 (7) | 0 (0) | |||
| Esophagectomy | 5 (4) | 2 (3) | 1 (4) | |||
| Other solid organ transplant (no lung or heart transplant) | 4 (3) | 2 (3) | 1 (4) | |||
| Orthopedic surgery | 3 (2) | 2 (3) | 0 (0) | |||
| Other patient type | 6 (5) | 3 (4) | 1 (4) | |||
| Site of first positive culture, No. (%) | ||||||
| Respiratory | 86 (68) | 56 (79) | 9 (38) | |||
| Bronchoalveolar lavage | 67 (53) | 45 (63) | 6 (25) | |||
| Blood | 15 (12) | 4 (6) | 6 (25) | |||
| Pleural fluid | 8 (6) | 4 (6) | 2 (8) | |||
| Sternal wound | 5 (4) | 0 (0) | 5 (21) | |||
| Bone | 3 (2) | 2 (3) | 0 (0) | |||
| VAD driveline site | 3 (2) | 0 (0) | 2 (8) | |||
| Peritoneal fluid | 2 (2) | 2 (3) | 0 (0) | |||
| Other | 4 (3) | 3 (4) | 0 (0) | |||
| Time of diagnosis in solid organ transplant recipients | ||||||
| Median days from transplant surgery to positive culture (IQR) | ||||||
| All solid organ transplant recipients (n = 70) | 41 (12–114) | 18 (8–73) | 105 (59–352) | |||
| Lung transplant (n = 58) | 34 (11–94) | 13 (6–47) | 80 … | |||
| Heart transplant (n = 8) | 43 (18–106) | 18 … | 95 … | |||
| Other solid organ transplant (n = 4) | 169 … | 483 … | 144 … | |||
| Positive culture during index transplant surgery hospitalization, no./total No. (%) | ||||||
| All solid organ transplant recipients | 43/70 (61) | 33/45 (73) | 3/10 (30) | |||
| Lung transplant | 36/58 (62) | 29/39 (74) | 1/5 (20) | |||
| Heart transplant | 6/8 (75) | 4/4 (100) | 2/4 (50) | |||
| Other solid organ transplant | 1/4 (25) | 0/2 (0) | 0/1 (0) | |||
Patients with a positive culture obtained on day 1 or day 2 of admission were excluded unless they had previously been hospitalized within 30 days prior to the date of the first positive culture.
Abbreviations: IQR, interquartile range; VAD, ventricular assist device.