Table 1.
Summary of GATA1 Immunoreactivity in Acute Leukemia and Other Hematologic Disorders
| Diagnosis | No. of Cases | GATA1 Reactivity in Blasts, No. |
|---|---|---|
| Normal | 3 | 0 |
| Acute myeloid leukemias | ||
| Acute promyelocytic leukemia | 7 | 0 |
| Acute myelomonocytic leukemia | 4 | 0 |
| Acute myelomonocytic leukemia with eosinophilia | 5 | 0 |
| Acute monoblastic leukemia | 3 | 0 |
| Acute monocytic leukemia | 8 | 0 |
| Pure erythroleukemia | 14 | 14 |
| Acute erythroleukemia, erythroid/myeloid type | 6 | 0 |
| Acute megakaryoblastic leukemia | 5 | 5 |
| Acute lymphoblastic leukemias | ||
| B-ALL | 8 | 0 |
| T-ALL | 5 | 0 |
| Other disorders | ||
| Chronic myelogenous leukemia | 5 | Weak, rare cellsa |
| Systemic mastocytosis | 3 | Strong, intermediate |
| Hypereosinophilic syndrome | 2 | Weak, intermediateb |
| Plasma cell neoplasm | 3 | None |
| Metastatic carcinoma | 3 | None |
B-ALL, B-acute lymphoblastic leukemia; GATA1, GATA binding factor 1; T-ALL, T-acute lymphoblastic leukemia.
a
Likely representing eosinophilic myeloid elements.
b
Eosinophilic myeloid elements.