Table 4.
rs9722 | rs2239574 | rs881827 | rs9984765 | rs1051169 | |
---|---|---|---|---|---|
p-Valuea allele | *4.1 × 10 −6 | 0.448 | 0.043 | 0.007 | 0.028 |
p-Valuea genotype | *5.0 × 10 −5 | 0.233 | 0.131 | 0.018 | 0.049 |
p-Valueb allele | *0.003 | 0.912 | 0.132 | 0.016 | 0.038 |
p-Valueb genotype | 0.015 | 0.731 | 0.289 | 0.034 | 0.079 |
ORc | 2.9 (1.8–4.7) | 1.1 (0.8–1.6) | 1.4 (1.0–2.0) | 1.6 (1.1–2.1) | 1.4 (1.0–1.9) |
aEarly onset PD (≤50 years) compared to late onset PD (> 50 years). bEarly onset PD compared to controls. cOR (95% confidence interval) for early onset PD compared to controls. Significant (p < 0.05) results are shown in bold. With Bonferroni correction for multiple testing (analyses of 5 SNPs and 3 comparisons; controls versus all PD patients, controls versus early onset PD and early onset versus late onset PD) significant (p < 0.0033) results are shown by *. P-values were calculated from Chis-square test and ORs were calculated using logistic regression