Table 1.
Differences in full length amino acid sequences encoded by KIR2DS5*001, KIR2DS5*002, and 14 mutant constructs
| Codon | −20 | 111 | 164 | 174 |
|---|---|---|---|---|
| KIR2DS5*001 (not expressed on surface) | L | P | S | A |
| KIR2DS5*002 (expressed on surface) | S | S | F | T |
| Mutant 1 | S | – | – | – |
| Mutant 2 | – | S | – | – |
| Mutant 3 | – | – | F | – |
| Mutant 4 | – | – | – | T |
| Mutant 5 | – | S | F | T |
| Mutant 6 | S | – | F | T |
| Mutant 7 | S | S | – | T |
| Mutant 8 | S | S | F | – |
| Mutant 9 | – | S | – | T |
| Mutant 10 | S | – | F | – |
| Mutant 11 | – | S | F | – |
| Mutant 12 | S | – | – | T |
| Mutant 13 | S | S | – | – |
| Mutant 14 | – | – | F | T |
a
Dash indicates sequence is identical to the sequence of KIR2DS5*001.