TABLE 1.
Run No. | Sample No. | LLOQ 0.0500 (ng/mg hair) | Low 0.150 (ng/mg hair) | Medium 1.00 (ng/mg hair) | High 14.0 (ng/mg hair) | Run No. | Intraday statistics | LLOQ 0.0500 (ng/mg hair) | Low 0.150 (ng/mg hair) | Medium 1.00 (ng/mg hair) | High 14.0 (ng/mg hair) |
---|---|---|---|---|---|---|---|---|---|---|---|
1 | 0.0470 | 0.153 | 1.07 | 14.3 | Mean | 0.0471 | 0.151 | 1.03 | 14.0 | ||
2 | 0.0483 | 0.149 | 1.08 | 14.3 | SD | 0.0013 | 0.003 | 0.04 | 0.4 | ||
1 | 3 | 0.0474 | 0.154 | 1.02 | 14.1 | 1 | %CV | 2.76 | 1.99 | 3.88 | 2.86 |
4 | 0.0452 | 0.150 | 1.03 | 14.1 | %RE | −5.80 | +0.667 | +3.00 | 0.00 | ||
5 | 0.0463 | 0.147 | 1.01 | 13.8 | n | 6 | 6 | 6 | 6 | ||
6 | 0.0486 | 0.152 | 0.981 | 13.3 | |||||||
1 | 0.0540 | 0.159 | 1.04 | 14.2 | Mean | 0.0540 | 0.153 | 0.990 | 13.9 | ||
2 | 0.0563 | 0.151 | 0.993 | 13.4 | SD | 0.0034 | 0.003 | 0.049 | 0.5 | ||
2 | 3 | 0.0524 | 0.149 | 1.05 | 14.7 | 2 | %CV | 6.30 | 1.96 | 4.95 | 3.60 |
4 | 0.0506 | 0.153 | 0.966 | 13.8 | %RE | +8.00 | +2.00 | −1.00 | −0.714 | ||
5 | 0.0596 | 0.153 | 0.972 | 13.3 | n | 6 | 6 | 6 | 6 | ||
6 | 0.0513 | 0.155 | 0.921 | 13.9 | |||||||
1 | 0.0432 | 0.140 | 0.945 | 13.0 | Mean | 0.0427 | 0.148 | 1.04 | 13.9 | ||
2 | 0.0415 | 0.142 | 1.04 | 13.5 | SD | 0.0008 | 0.006 | 0.06 | 0.7 | ||
3 | 3 | 0.0431 | 0.146 | 1.02 | 13.5 | 3 | %CV | 1.87 | 4.05 | 5.77 | 5.04 |
4 | 0.0437 | 0.152 | 1.11 | 14.8 | %RE | −14.6 | −1.33 | +4.00 | −0.714 | ||
5 | 0.0420 | 0.150 | 1.06 | 14.5 | n | 6 | 6 | 6 | 6 | ||
6 | 0.0428 | 0.156 | 1.06 | 14.3 | |||||||
Interday statistics | Intraday ranges | ||||||||||
Theoretical conc. | 0.0500 | 0.150 | 1.00 | 14.0 | |||||||
Mean | 0.0480 | 0.151 | 1.02 | 13.9 | Mean | 0.0427–0.0540 0.148–0.153 | 0.990–1.04 | 13.9–14.0 | |||
SD | 0.0052 | 0.005 | 0.05 | 0.5 | SD | 0.0008–0.0034 0.003–0.006 | 0.04–0.06 | 0.4–0.7 | |||
%CV | 10.8 | 3.31 | 4.90 | 3.60 | %CV | 1.87–6.30 | 1.96–4.05 | 3.88–5.77 | 2.86–5.04 | ||
%RE | −4.00 | +0.667 | +2.00 | −0.714 | %RE | −14.6 to +8.00 | −1.33 to +2.00 | −1.00 to +4.00 | −0.714 to 0.00 | ||
n | 18 | 18 | 18 | 18 | n | 6 | 6 | 6 | 6 |