Fig. 2.

Octave band noise exposure at 101 dB SPL causes PTS in male and female mice. a Comparison of baseline hearing threshold between males and females. Female mice present a lower threshold at 32 kHz. b Hearing thresholds were compared between baseline, 24 h, and 15 days post-noise exposure in males (top) and females (bottom). At 24 h and 15 days post-noise exposure, significant compound threshold shifts are seen across all frequencies tested in both males and females. (*p < 0.05; ***p < 0.001; **** < 0.0001; ns non-significant)