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. 2018 Mar 12;9:12. doi: 10.1186/s13293-018-0171-0

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Protective effect of SAHA on NIHL—both sexes combined. Threshold shifts were compared between SAHA- and vehicle-treated animals at 24 h (a) and 15 days (b) post-noise exposure. The dots indicate individual ear threshold shifts; the upper and lower whiskers indicate the maximum and minimum shifts, respectively. a CTS values suggested a protective effect of SAHA at 16 kHz (*p = 0.007). b PTS values suggested a protective effect of SAHA at 16 kHz (*p = 0.0095) and 24 kHz (**p = 0.0024)