Fig. 2.

Motor and somatosensory cortex leg, hand and face region sampling. Identification of motor and somatosensory cortical regions of interest by the sulci (solid yellow lines) on the dorsal and lateral surfaces (a). Dashed yellow lines (a) represents the leg, hand and face regions excised for analysis. Corresponding MR structural images of paracentral lobule (b), hand knob (c) and lateral face (d) areas are highlighted in blue, yellow and pink, respectively. The hand knob recognised by the inverted omega on the central sulcus of the MR structural image (c). Major sulci were used as anatomical landmarks for guided sampling. Annotations—1: superior frontal sulcus, 2: inferior frontal sulcus, 3: pre-central sulcus, 4: post-central sulcus, 5: paracentral sulcus, 6: cingulate sulcus, 6*: marginal segment of the cingulate sulcus, CS central sulcus, arrow: interhemispheric fissure where leg region sampled on the paracentral lobule