Table 3.
Shared pfubp1 mutations observed in the isolates from the three sites. Mutations indicated in bold are known delayed clearance genotypes
| Nucleotide position | Nucleotide change | Amino acid position and change |
|---|---|---|
| 4383 | CCT to ACC | P1461T |
| 4386 | TAT to TTA | Y1462L |
| 4389 | CGT to TCG | R1463S |
| 4392 | AAA to TAA | K1464a |
| 4461 | ATA to ATC | I1487I |
| 4461 | ATA to ACC | I1487T |
| 4466 | ATG to ACG | M1489T |
| 4502 | TAT to TTT | Y1501F |
| 4504 | AAA to TAA | K1502a |
| 4509 | AAT to ATT | N1503I |
| 4509 | AAT to ATG | N1503M |
| 4527 | GAA to GAC | E1509D |
| 4554 | AAC to TAT | N1518Y |
| 4557 | GAA to GAC | E1519D |
| 4561 | TAT to AAT | Y1521N |
| 4575 | GAC to GAA | D1525E |
| 4581 | TAT to TTT | Y1527F |
| 4581 | TAT to AAT | Y1527N |
| 4584 | GAA to GAC | E1528D |
| 4599 | TAT to TAC | Y1533Y |
| 4602 | GAT to GAA | D1534E |
| 4608 | TAC to TCC | Y1536S |
| 4611 | AAA to TTT | K1537F |
| 4609 | AAA to TTA | K1537L |
| 4611 | AAA to TAC | K1537Y |
| 4617 | GAT to GAC | D1539D |
| 4623 | AAA to CTT | K1541L |
| 4623 | AAA to AAT | K1541N |
| 4626 | AAT to GAT | N1542D |
| 4629 | CAA to CAT | Q1543H |
| 4632 | CAT to CTT | H1544L |
| 4632 | CAT to CCT | H1544P |
| 4632 | AAA to AAT | K1544N |
| 4641 | CCA to CCT | P1547P |
| 4647 | TAT to TAG | Y1549a |
| 4647 | TAT to TTT | Y1549F |
| 4646 | TAT to TTG | Y1549L |
| 4650 | GAT to ATT | D1550I |
| 4650 | GAT to AAT | D1550N |
| 4651 | AAT to GGT | N1551G |
| 4653 | AAT to ATT | N1551I |
| 4653 | AAT to CTT | N1551L |
| 4656 | ATT to ATG | I1552M |
| 4659 | AAT to AAC | N1553N |
| 4667 | TAC to TGC | Y1556C |
| 4674 | AAT to GAT | N1558D |
| 4679 | AAT to ATA | N1560I |
| 4680 | AAT to AAA | N1560K |
| 4683 | AAA to AAG | K1561K |
| 4692 | GAG to GAC | E1564D |
| 4695 | TTC to GGC | F1565G |
| 4694 | TTC to CAA | F1565Q |
| 4765 | AAA to TAA | K1589a |
aStop codon