Table 2.
Allele and genotype analysis of rs10759, rs531564, and rs951436 between cases and controls
| SNPs | N | Allele (%) | χ2 | p-value | MAF (%) | Genotype (%) | χ2 | p-value | OR (95% CI) | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| rs10759 | G | T | GG | GT | TT | |||||||
| Case | 219 | 257 (0.587) | 181 (0.413) | 2.811 | 0.094 | 0.44 | 74 (0.338) | 109 (0.498) | 36 (0.164) | 2.983 | 0.225 | 0.78 (0.51–1.19) |
| Control | 435 | 468 (0.538) | 402 (0.462) | 121 (0.278) | 226 (0.520) | 88 (0.202) | ||||||
| rs531564 | C | G | CC | CG | GG | |||||||
| Case | 220 | 76 (0.173) | 364 (0.827) | 1.167 | 0.326 | 0.173 | 6 (0.027) | 64 (0.291) | 150 (0.682) | 1.148 | 0.563 | 1.08 (0.39–2.96) |
| Control | 435 | 132 (0.152) | 738 (0.848) | 11 (0.025) | 110 (0.253) | 314 (0.722) | ||||||
| rs951436 | A | C | AA | AC | CC | |||||||
| Case | 220 | 212 (0.482) | 228 (0.518) | 2.379 | 0.123 | 0.41 | 50 (0.227) | 112 (0.509) | 58 (0.264) | 4.002 | 0.135 | 1.08 (0.73–1.60) |
| Control | 436 | 381 (0.437) | 491 (0.563) | 93 (0.213) | 195 (0.447) | 148 (0.339) | ||||||
Abbreviations: MAF, minor allele frequency; OR, odds ratio; 95% CI, 95% confidence interval; SNPs, single nucleotide polymorphisms.