Table 5.
Influence of S1–S4 on the metabolic activity of the tumor cell populations, expressed as linear regression of the changes in reducing potential within a 24-h exposure. The deviation of the slope from 0 is an indicator of the cellular metabolic decline, and it is significant when p < 0.05.
| Cell Line | Deviation from 0 | Material S1 | Material S2 | Material S3 | Material S4 |
|---|---|---|---|---|---|
| HepG2 | Hillslope | −749.6 ± 481.2 | −352.2 ± 292.4 | −534.3 ± 425.7 | −1066 ± 328.2 |
| p value | 0.1416 | 0.2483 | 0.2299 | 0.0058 | |
| Hep3B | Hillslope | −1048 ± 145.2 | −1267 ± 23.2 | −1436 ± 167.0 | −1462 ± 185.3 |
| p value | < 0.0001 | < 0.0001 | < 0.0001 | 0.0002 | |
| SK-Hep-1 | Hillslope | −1215 ± 236.1 | −1326 ± 234.2 | −1876 ± 358.2 | −1116 ± 308.6 |
| p value | 0.0001 | < 0.0001 | 0.0001 | 0.0028 | |
| DLD-1 | Hillslope | −360.9 ± 209.1 | −719.3 ± 129.1 | −916.2 ± 216.6 | −1400 ± 319.7 |
| p value | 0.0610 | 0.0063 | 0.0106 | 0.0005 | |
| HT-29 | Hillslope | −1082 ± 278.3 | −1066 ± 286.3 | −2063 ± 277.8 | −1263 ± 212.1 |
| p value | 0.0013 | 0.0019 | < 0.0001 | < 0.0001 | |
| COLO320 | Hillslope | −369.0 ± 227.8 | −278.8 ± 188.4 | −683.7 ± 112.0 | −1195 ± 236.5 |
| p value | 0.1276 | 0.1612 | < 0.0001 | 0.0002 |