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. Author manuscript; available in PMC: 2019 Mar 25.
Published in final edited form as: Eur J Med Chem. 2018 Feb 12;148:195–209. doi: 10.1016/j.ejmech.2018.02.031

Table 2.

Minimum inhibitory concentration (MIC in μg/mL) and minimum bactericidal concentration (MBC μg/mL) of active compounds screened against additional S. aureus isolates.

S. aureus NRS107 MRSA NRS119 MRSA NRS123 (USA400) VRS10 (VRSA) VRS11a (VRSA) VRS12 (VRSA)
Compound Name MIC MBC MIC MBC MIC MBC MIC MBC MIC MBC MIC MBC
5 2 2 1 2 1 4 1 2 1 2 2 2
6 16 16 4 4 2 2 2 2 1 2 2 2
7 2 2 1 2 2 2 2 2 1 4 2 2
8 2 4 4 4 2 2 2 4 4 4 2 2
9 2 2 2 2 2 2 2 4 2 2 2 2
10 1 1 1 1 ≤ 0.5 2 1 2 ≤ 0.5 ≤ 0.5 1 1
11 2 4 2 2 2 2 2 2 1 2 2 2
12 4 8 1 4 4 4 2 4 0.5 2 2 4
13 2 4 2 2 4 16 4 4 2 8 4 4
17 16 32 32 32 16 32 4 8 8 8 16 16
21 16 32 16 32 16 32 8 64 8 16 16 32
23 2 4 2 2 4 16 4 4 4 4 4 8
Vancomycin 1 1 1 1 1 1 512 512 >512 >512 16 256