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In vivo PK parameters of compound 9 in rat after single IV bolus injection.
| t1/2 (h) | CL (L/hr) | AUC mg.hr/L | V (L) | Vdss (L) | |
|---|---|---|---|---|---|
| 9 | 4.43 | 5.36 | 0.69 | 18.46 | 5.51 |
t1/2: half-life; CL: clearance; Vb: volume of distribution in 2nd compartment (peripheral tissues); Vdss: volume of distribution at the steady state
