Table 3.

Imaging parameters for subjects stratified by mean blood or sputum eosinophils (Eos; cutoff 200/µL, or cutoff 1·25%, respectively).

Variable	Blood Eos<200/µL (N=1262)	Blood Eos≥200/µL (N=1237)	P value*	Sputum Eos<1.25% (N=656)	Sputum Eos≥1.25% (N=171)	P value*
DENSITY MEASURES
TLC Left Upper Lobe %<−950 HU	3·22 (1·11 –11·84)	3·77 (1·20 –11·50)	0·66	2·24 (0·89 – 5·74)	2·88 (1·09 – 7·65)	0·046
TLC Right Upper Lobe %<−950 HU	2·78 (0·72 –12·97)	2·87 (0·73 –11·96)	0 76	1·73 (0·6 – 5·58)	2·43 (0·9 – 7·24)	0·011
TLC Left Lower Lobe %<–950 HU	2·09 (0·81–7·09)	2·42 (0·88–7·5)	0·23	1·60 (0·72 – 3·78)	1·98 (0·76 – 5·32)	0·044
RV BOTH Lungs %<−856 HU	17·4 (6·71–39·38)	18·91 (7·39–40·71)	0·28	12·52 (5·34–25·27)	17·20 (8·57–33·13)	0·001
PRM functional small airway disease	14 (4–33)	15 (4–34)	0·21	9 (3–22)	13 (6–26)	0·011
AIRWAY MEASURES
AVG WALL THICK apical right upper lobe	1·26 (1·15–1·37)	1·28 (1·16–1·39)	0·032	1·28 (1·18–1·38)	1·29 (1·19–1·42)	0·08
Taper Ratio - apical right upper lobe	0·038 (−0·01–0·086)	0·039 (−0·01–0·09)	0·87	0·03 (−0·01–0·08)	0·03 (−0·01–0·08)	0·93

^*Mann-Whitney rank sum test for continuous variables, results as median (25–75% interquartile range).