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. 2017 Jun 20;65(8):1260–1265. doi: 10.1093/cid/cix558

Figure 2.

Figure 2.

Cytokine (interleukin [IL]; interferon [IFN]) response in patients with dengue virus (DENV) serotype 2 and Zika virus (ZIKV) during primary and secondary dengue infections. A, Cytokine levels measured in DENV 2-positive patients with primary (immunoglobulin G–negative [IgG–]) DENV infection (n = 06) and secondary (immunoglobulin G–positive [IgG+]) DENV infection (n = 14). The Mann-Whitney U test demonstrated a significant P value in the cases of IL-1β (*P = .0039), IL-6 (**P = .0133), IL-8 (***P = .0477), and IL-9 (****P = .0391). B, Cytokine levels measured in ZIKV-positive patients with primary (IgG–) DENV infection (n = 10) and secondary (IgG+) DENV infection (n = 35). The Mann-Whitney U test demonstrated no significant P value.