Table 2.

Planned or Ongoing Tuberculosis Prevention and Treatment Studies in Pregnant Women

Triala	Phase	TB Type	Study Purpose
IMPAACT P1078 NCT01494038	4	DS-TBI	To evaluate antepartum vs postpartum isoniazid preventive therapy in pregnant women with HIV
IMPAACT P2001 NCT02651259	1/2	DS-TBI	To evaluate the pharmacokinetics and safety of rifapentine and isoniazid preventive therapy in pregnant women with and without HIV
IMPAACT P1026s NCT00042289	4	DS-/DR-TB	To evaluate the pharmacokinetics of first- and second-line TB drugs in pregnant women with and without HIV

Abbreviations: DR-TB, drug-resistant tuberculosis; DS-TBI, drug-sensitive tuberculosis infection; HIV, human immunodeficiency virus; IMPAACT, International Maternal Pediatric Adolescent AIDS Clinical Trials Network.

^aNational Institutes of Health clinical trial identifiers are shown; for more information, go to ClinicalTrials.gov.