Table 2. SNPs found in recurrent somatic copy number aberrations or within 5 gene signatures predicting PCa aggressiveness.
| Location | SNP | Somatic copy number aberration (SCNA) | Gene from gene signature |
|---|---|---|---|
| 3p | rs2660753, rs7652331, rs1545985, | gain 3p | - |
| 5q14.3 | rs35148638, rs2939244 | loss 5q | - |
| 6q25.3 | rs9364554 | loss 6q | - |
| 8p21.2 | rs1512268 | loss 8p22 | - |
| 8q24.21 | rs6983267, rs1447295, rs4242382, rs10090154 | gain 8q24 | - |
| 11q13.3 | rs10896449, rs11228565 | gain 11q13 | TMEM132A [83] |
| 13q12.2 | rs9508016 | loss 13q | ZIC2, ZIC5 [87] |
| 17q | rs11649743, rs6504145, rs1859962 | loss 17q | - |
| 19q13 | rs11672691, rs62113212, rs266870, rs1058205, rs2735839, rs103294 | - | KEAP1 [86], UPK1A [85], APOC1 [83] |
| 20q13.33 | rs2427345 | - | MYBL2, UBE2C [84] |
Table containing a subset of genes from 5 gene signatures predicting PCa aggressiveness, Wu et al [84], Ross et al [86], Bibikova et al [88], and Sahabi et al [85]. The respective chromosome arm and when applicable, cytoband for each gene along with recurrent SCNAs associated with PCa [21] within the same locus. A subset of SNPs associated with aggressive PCa within the same locus are also shown.