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. Author manuscript; available in PMC: 2018 Mar 13.
Published in final edited form as: Eur J Nucl Med Mol Imaging. 2015 Jan 29;42(5):716–724. doi: 10.1007/s00259-014-2975-4

Figure 1.

Figure 1

Subject stratification among 371 MCI subjects with contemporaneous [18F]-AV45-PET, FDG-PET and T1w MRI at ADNI-GO/2 baseline assessment. All subjects were first categorized as positive or negative according to their amyloid-PET status [19] for the voxel-wise analysis (left branch). Subsequently, the Neuropsychiatric Inventory Questionnaire (NPI-Q; depression item #4) was used to identify subclinically depressed and non-depressed study-groups. The 366 subjects who received clinical follow-up were used for the conversion analysis (right branch) with respect to Aß and depression status.