Figure 4.
Prediction −2 × loglikelihood averaged over 20 simulation replicates for binary traits in polygenic scenarios (P7,...,P12). Black dashed line (ST), average of mean −2 × loglikelihood for training data (PSEtr) for predictive models from smooth-threshold multivariate genetic prediction at each p-value threshold in minus log10-scale (x-axis). Black dotted line (ST.P), average of prediction −2 × loglikelihood for test data (PSEte) for predictive model from smooth-threshold multivariate genetic prediction trained on the training data. Red solid line (CpST), average of the proposed Cp-type criterion (an approximate unbiased estimator of the black dashed line).