Table 5.
Significant shortest paths at amin = 0.3 and α1 = 0.001. Paths that include genome-wide significant SNPs were excluded. Pmarg, marginal association p-value. Pmult, multiple regression p-value applied to each path. SNPs in each path are ordered so that the first SNP is adjacent to the phenotype and the last SNP is tested for association. SNPs tested in each path are emphasized in bold.
| Significant path | CHR | SNP | BP | Pmarg | Pmult |
|---|---|---|---|---|---|
| 1 | 5 | rs2963327 | 8987159 | 2.0e-04 | 8.1e-08 |
| 1 | 5 | rs2963345 | 8962508 | 3.2e-03 | 7.1e-03 |
| 1 | 5 | rs6870451 | 8991885 | 9.3e-02 | 1.4e-06 |
| 2 | 5 | rs2963327 | 8987159 | 2.0e-04 | 7.8e-08 |
| 2 | 5 | rs2963344 | 8962428 | 3.7e-03 | 1.1e-02 |
| 2 | 5 | rs6870451 | 8991885 | 9.3e-02 | 2.0e-06 |
| 3 | 5 | rs2963327 | 8987159 | 2.0e-04 | 7.7e-08 |
| 3 | 5 | rs2963345 | 8962508 | 3.2e-03 | 8.0e-03 |
| 3 | 5 | rs11955429 | 8994715 | 7.8e-02 | 1.6e-06 |
| 4 | 5 | rs2963327 | 8987159 | 2.0e-04 | 7.0e-08 |
| 4 | 5 | rs2963344 | 8962428 | 3.7e-03 | 1.3e-02 |
| 4 | 5 | rs11955429 | 8994715 | 7.8e-02 | 2.3e-06 |
| 5 | 5 | rs2963337 | 8988632 | 1.5e-04 | 4.0e-08 |
| 5 | 5 | rs2963345 | 8962508 | 3.2e-03 | 7.0e-03 |
| 5 | 5 | rs6870451 | 8991885 | 9.3e-02 | 8.6e-07 |
| 6 | 5 | rs2963337 | 8988632 | 1.5e-04 | 3.9e-08 |
| 6 | 5 | rs2963344 | 8962428 | 3.7e-03 | 1.1e-02 |
| 6 | 5 | rs6870451 | 8991885 | 9.3e-02 | 1.3e-06 |
| 7 | 5 | rs2963337 | 8988632 | 1.5e-04 | 3.8e-08 |
| 7 | 5 | rs2963345 | 8962508 | 3.2e-03 | 7.9e-03 |
| 7 | 5 | rs11955429 | 8994715 | 7.8e-02 | 9.9e-07 |
| 8 | 5 | rs2963337 | 8988632 | 1.5e-04 | 3.5e-08 |
| 8 | 5 | rs2963344 | 8962428 | 3.7e-03 | 1.2e-02 |
| 8 | 5 | rs11955429 | 8994715 | 7.8e-02 | 1.4e-06 |