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. 2018 Mar 13;13(3):e0193729. doi: 10.1371/journal.pone.0193729

Table 1. Prevalence of subjects with a long-term disease at 14 years of age.

Category Group Conditions All (N = 61,119) Females (N = 29,860) Males (N = 31,259)
n Pr, % (95%CI) n Pr, % (95%CI) n Pr, % (95%CI)
All All All 2,019 3.30 (3.16;3.44) 831 2.78 (2.59;2.97) 1,188 3.80 (3.59;4.01)
Mental All All 498 0.81 (0.74;0.88) 129 0.43 (0.36;0.50) 369 1.18 (1.06;1.30)
Psychiatric diseases Autism spectrum disorders 166 0.27 (0.23;0.31) 39 0.13 (0.09;0.17) 127 0.41 (0.34;0.48)
Specific personality disorders 120 0.20 (0.16;0.24) 28 0.09 (0.06;0.12) 92 0.29 (0.23;0.35)
Psychotic disorders 22 0.04 (0.02;0.06) 10 0.03 (0.01;0.05) 12 0.04 (0.02;0.06)
Neurotic, emotional, mood disorders 135 0.22 (0.18;0.26) 37 0.12 (0.08;0.16) 98 0.31 (0.25;0.37)
Other psychological development disorder 54 0.09 (0.07;0.11) 14 0.05 (0.02;0.08) 40 0.13 (0.09;0.17)
Other psychiatric affections 1 0.00 (0.00;0.00) 1 0.00 (0.00;0.00) 0 0.00 (0.00;0.00)
Non-complex All All 671 1.10 (1.02;1.18) 278 0.93 (0.82;1.04) 393 1.26 (1.14;1.38)
Endocrine and metabolic diseases Type 1 and type 2 diabetes 114 0.19 (0.16;0.22) 48 0.16 (0.11;0.21) 66 0.21 (0.16;0.26)
Respiratory diseases Persistent asthma 235 0.38 (0.33;0.43) 88 0.29 (0.23;0.35) 147 0.47 (0.39;0.55)
Other serious chronic respiratory insufficiency 17 0.03 (0.02;0.04) 8 0.03 (0.01;0.05) 9 0.03 (0.01;0.05)
Vascular diseases Chronic arteriopathies with ischemic manifestations 3 0.00 (0.00;0.00) 3 0.01 (0.00;0.02) 0 0.00 (0.00;0.00)
Severe hypertension 3 0.00 (0.00;0.00) 1 0.00 (0.00;0.00) 2 0.01 (0.00;0.02)
Heart disease Severe congenital heart disease 110 0.18 (0.15;0.21) 48 0.16 (0.11;0.21) 62 0.20 (0.15;0.25)
Other heart diseases 23 0.04 (0.02;0.06) 12 0.04 (0.02;0.06) 11 0.04 (0.02;0.06)
Kidney diseases Severe chronic kidney disease and primitive nephrotic syndrome 47 0.08 (0.06;0.10) 24 0.08 (0.05;0.11) 23 0.07 (0.04;0.10)
Liver diseases Active chronic liver disease and cirrhosis 15 0.02 (0.01;0.03) 8 0.03 (0.01;0.05) 7 0.02 (0.00;0.04)
Inflammatory Bowel Disease Progressive Crohn's disease and ulcerative colitis 26 0.04 (0.02;0.06) 13 0.04 (0.02;0.06) 13 0.04 (0.02;0.06)
Malignancies Malignant tumor, malignant disease of lymphatic tissue or blood 78 0.13 (0.10;0.16) 25 0.08 (0.05;0.11) 53 0.17 (0.12;0.22)
Complex All All 850 1.39 (1.30;1.48) 424 1.42 (1.29;1.55) 426 1.36 (1.23;1.49)
Chromosome abnormalities Down syndrome 45 0.07 (0.05;0.09) 19 0.06 (0.03;0.09) 26 0.08 (0.05;0.11)
Other chromosome abnormalities 15 0.02 (0.01;0.03) 10 0.03 (0.01;0.05) 5 0.02 (0.00;0.04)
Neurological and muscular diseases Cerebral palsy 89 0.15 (0.12;0.18) 37 0.12 (0.08;0.16) 52 0.17 (0.12;0.22)
Paraplegia 11 0.02 (0.01;0.03) 6 0.02 (0.00;0.04) 5 0.02 (0.00;0.04)
Severe epilepsy 94 0.15 (0.12;0.18) 45 0.15 (0.11;0.19) 49 0.16 (0.12;0.20)
Other serious neurological and muscular diseases 72 0.12 (0.09;0.15) 30 0.10 (0.06;0.14) 42 0.13 (0.09;0.17)
Mental retardation Mental retardation 152 0.25 (0.21;0.29) 48 0.16 (0.11;0.21) 104 0.33 (0.27;0.39)
Immunodeficiencies Severe primary immunodeficiency requiring prolonged treatment 9 0.01 (0.00;0.02) 1 0.00 (0.00;0.00) 8 0.03 (0.01;0.05)
HIV infection 15 0.02 (0.01;0.03) 6 0.02 (0.00;0.04) 9 0.03 (0.01;0.05)
Medullary deficiencies and other chronic cytopenias 3 0.00 (0.00;0.00) 1 0.00 (0.00;0.00) 2 0.01 (0.00;0.02)
Hemolysis Hemoglobinopathies 17 0.03 (0.02;0.04) 6 0.02 (0.00;0.04) 11 0.04 (0.02;0.06)
Other constitutional chronic hemolysis, acquired hemolysis 5 0.01 (0.00;0.02) 3 0.01 (0.00;0.02) 2 0.01 (0.00;0.02)
Rheumatologic and systemic diseases Progressive rheumatoid arthritis 5 0.01 (0.00;0.02) 2 0.01 (0.00;0.02) 3 0.01 (0.00;0.02)
Juvenile arthritis 16 0.03 (0.02;0.04) 8 0.03 (0.01;0.05) 8 0.03 (0.01;0.05)
Progressive structural scoliosis 139 0.23 (0.19;0.27) 124 0.42 (0.35;0.49) 15 0.05 (0.03;0.07)
Vasculitis, systemic lupus erythematosus, systemic scleroderma 3 0.00 (0.00;0.00) 2 0.01 (0.00;0.02) 1 0.00 (0.00;0.00)
Hemorrhagic diseases Hemophilia and serious constitutional disorders of hemostasis 13 0.02 (0.01;0.03) 3 0.01 (0.00;0.02) 10 0.03 (0.01;0.05)
Purpura and other hemorrhagic conditions 11 0.02 (0.01;0.03) 3 0.01 (0.00;0.02) 8 0.03 (0.01;0.05)
Endocrine and metabolic diseases Inherited metabolic diseases requiring prolonged treatment 83 0.14 (0.11;0.17) 46 0.15 (0.11;0.19) 37 0.12 (0.08;0.16)
Respiratory diseases Cystic fibrosis 5 0.01 (0.00;0.02) 2 0.01 (0.00;0.02) 3 0.01 (0.00;0.02)
Vascular diseases Disabling stroke 21 0.03 (0.02;0.04) 11 0.04 (0.02;0.06) 10 0.03 (0.01;0.05)
  Multiple diseases Multiple diseases 27 0.04 (0.02;0.06) 11 0.04 (0.02;0.06) 16 0.05 (0.03;0.07)

Abbreviations: 95%CI, 95% confidence interval; Pr, prevalence