Table 1.
controls | CHF | |
---|---|---|
Age (yrs) | 50±3 | 54±2 |
Height (cm) | 176±1 | 180±2 |
Body Mass (kg) | 82±7 | 99±6 |
Quadriceps muscle mass (kg) | 2.1±0.2 | 2.2±0.2 |
NYHA class | - | II-III |
Peak Pulm. Cycle V̇O2 (l/min) | 2.34±0.30 | 1.66±0.21* |
Peak Pulm. Cycle V̇O2 (ml/kg/min) | 29.1±3.2 | 16.8±2.0* |
Maximum cycle work rate (W) | 170±23 | 101±13* |
Peak cycling leg V̇O2 (ml/min) | 479±35 | 336±36* |
Medications (fraction of users) | ||
Digoxin | 0/6 | 7/7 |
Diuretics | 0/6 | 7/7 |
Long-acting nitrates | 0/6 | 6/7 |
Statins | 0/6 | 5/7 |
Aspirin | 0/6 | 5/7 |
β-Blockers | 0/6 | 4/7 |
Warfarin | 0/6 | 3/7 |
ACE inhibitors | 0/6 | 5/7 |
Ca2+ channel blockers | 0/6 | 5/7 |
CHF, chronic heart failure; ACE, angiotensin-converting enzyme.
Anthropometric data and severity of disease (NYHA class) in controls and CHF patients. Work rate and pulmonary V̇O2 at maximum cycle ergometric exercise, together with peak leg V̇O2 at maximum KE exercise, are reported. The type of medications taken by CHF patients is also listed. Data are expressed as mean ± SE;
P<0.05.