Skip to main content
. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Nanomedicine. 2017 Jun 30;13(7):2359–2369. doi: 10.1016/j.nano.2017.06.014

Figure 7. Temporal patterns of neuronal Cy5-D-NAC uptake varied among hippocampal regions, and in DG uptake was greater at the onset of rewarming.

Figure 7

(A) In CA1, after adjusting for injury, uptake of the dendrimer varied as a function of time (p < 0.05), with decreased uptake in mice injected 6 h after HI. (B) No significant differences in uptake were observed in CA3. (C) In DG, uptake by neurons showed an interaction of injection time and temperature (p < 0.05); uptake of Cy5-D-NAC was greater in hypothermic animals when administered 6 h after HI, at the onset of rewarming (p < 0.05, estimated marginal means ± s.e.m.).