Table 4.
Classification | Lotions | Creams | Ointments | Gel |
---|---|---|---|---|
Phase | Oil in water (O/W) | Water in oil (W/O) (hydrophobic) or O/W (hydrophilic) | W/O (hydrophobic)/ or O/W (hydrophilic) | Hydrophobic or hydrophilic |
Preparation | O/W prepared with emulsifiers to enhance spread ability | O/W creams are prepared at elevated temperature, followed by reduction to room temperature for internal phase to solidify oil and water (50% each) | Does not contain enough water to separate into second phase at room temperature. Most contain 80% oil and 20% water | Has liquid phase in a three dimensional polymeric matrix with physical or sometimes chemical cross linkage with appropriate gelling agent |
Composition | Oil, Water, Propylene glycol | W/O: emulsifier such as monoglycerides, sorbitan esters and wool fat O/W: emulsifying agents such as sodium or triethanolamine soaps, sulfated fatty alcohols and polysorbates. When necessary may be combined with W/O emulsifying agents |
W/O: water insoluble hydrocarbons such as paraffin, vegetable oil, animal fats, waxes, synthetic glycerides and polyalkysiloxanes O/W: mixtures of liquid and solid polyethylene glycols (macrogols) |
Hydrophobic gel (oleogel): Liquid paraffin with polyethylene or fatty oils gelled with colloidal silica, alumunium, or zinc soaps Hydrophilic gel (hydrogel): water, glycerol or propylene glycol gelled with suitable agents such as tragacanth, starch, derivatives of cellulose, carboxy vinyl polymers and magnesium/alumunium silicates |
Properties | Non greasy, thinner, easily spreads to cover large areas | Esthetic. Made of heavier lipids | Greasy, glossy look following application Forming skin’s protective layer, particularly useful in low humidity (< 60%) environment |
Smooth finishing, non oily, non comedogenic, absorbs easily |
Usage | Daytime moisturizer for face and body. After shave lotions, for application on hairy areas | Night time moisturizers for face hand, and non hairy body parts To use when no occlusive effect is required |
Particularly beneficial when high degree of occlusive is required; Contraindicated for intertriginous and moisture bearing areas | To be used in intertriginous areas, easily absorbed, high acceptability for face, non comedogenic |
O/W, oil in water; W/O, water in oil