Table 1.
Characteristic | No CKD n= 356458 |
Stage 3 CKD n=339278 |
Stage 4 CKD n=15167 |
Stage 5 CKD n=2014 |
---|---|---|---|---|
Age, mean (SD) | 70.9 (6.3) | 75.1 (6.4)** | 75.6 (6.8)** | 73.5 (6.4)** |
Black Race, n (%) | 33299 (9.3%) | 18371 (5.4%)** | 1507 (9.9%)* | 423 (21.0%)** |
Body Mass Index, mean (SD) | 28.7 (5.1) | 28.7 (4.8) | 28.3 (5.1)** | 27.5 (4.9)** |
Current Smoking, n (%) | 80112 (22.5%) | 64687 (19.1%)** | 3085 (20.3%)** | 481 (23.9%)** |
Chronic Alcohol Use, n (%) | 65185 (18.3%) | 56457 (16.6%)** | 2507 (16.5%)** | 333 (16.5%)* |
Chronic Steroid use, n (%) | 5936 (1.7%) | 5664 (1.7%) | 305 (2.0%)* | 45 (2.2%) |
Rheumatoid Arthritis, n (%) | 2315 (0.7%) | 1750 (0.5%)** | 61 (0.4%)* | 6 (0.3%) |
Hyperthyroidism, n (%) | 4060 (1.1%) | 4794 (1.4%)** | 245 (1.6%)** | 33 (1.6%)* |
Diabetes, n (%) | 108647 (30.5%) | 124345 (36.7%)** | 7855 (51.8%)** | 1140 (56.6%)** |
Chronic Lung Disease, n (%) | 85937 (24.1%) | 90906 (26.8%)** | 4514 (29.8%)** | 585 (29.1%)** |
Chronic Liver disease, n (%) | 27378 (7.7%) | 25229 (7.4%)** | 1673 (11.0%)** | 401 (19.9%)** |
Malabsorption, n (%) | 1178 (0.3%) | 1453 (0.4%)** | 120 (0.8%)** | 67 (3.3%)** |
10-Yr Probability of Major Fracture (FRAX), mean (SD) | 5.5 (2.7) | 6.6 (3.0)** | 6.8 (3.3)** | 6.3 (3.5)** |
P value refers to comparison of each CKD Stage to the reference group (no CKD which is defined as estimated glomerular filtration rate ≥ 60ml/min/1.73m2).
P < .05.
P ≤ .0001.