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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: J Am Geriatr Soc. 2018 Jan 10;66(3):532–538. doi: 10.1111/jgs.15256

Table 1.

Cohort Characteristics by Chronic Kidney Disease Stage

Characteristic No CKD
n= 356458
Stage 3 CKD
n=339278
Stage 4 CKD
n=15167
Stage 5 CKD
n=2014
Age, mean (SD) 70.9 (6.3) 75.1 (6.4)** 75.6 (6.8)** 73.5 (6.4)**
Black Race, n (%) 33299 (9.3%) 18371 (5.4%)** 1507 (9.9%)* 423 (21.0%)**
Body Mass Index, mean (SD) 28.7 (5.1) 28.7 (4.8) 28.3 (5.1)** 27.5 (4.9)**
Current Smoking, n (%) 80112 (22.5%) 64687 (19.1%)** 3085 (20.3%)** 481 (23.9%)**
Chronic Alcohol Use, n (%) 65185 (18.3%) 56457 (16.6%)** 2507 (16.5%)** 333 (16.5%)*
Chronic Steroid use, n (%) 5936 (1.7%) 5664 (1.7%) 305 (2.0%)* 45 (2.2%)
Rheumatoid Arthritis, n (%) 2315 (0.7%) 1750 (0.5%)** 61 (0.4%)* 6 (0.3%)
Hyperthyroidism, n (%) 4060 (1.1%) 4794 (1.4%)** 245 (1.6%)** 33 (1.6%)*
Diabetes, n (%) 108647 (30.5%) 124345 (36.7%)** 7855 (51.8%)** 1140 (56.6%)**
Chronic Lung Disease, n (%) 85937 (24.1%) 90906 (26.8%)** 4514 (29.8%)** 585 (29.1%)**
Chronic Liver disease, n (%) 27378 (7.7%) 25229 (7.4%)** 1673 (11.0%)** 401 (19.9%)**
Malabsorption, n (%) 1178 (0.3%) 1453 (0.4%)** 120 (0.8%)** 67 (3.3%)**
10-Yr Probability of Major Fracture (FRAX), mean (SD) 5.5 (2.7) 6.6 (3.0)** 6.8 (3.3)** 6.3 (3.5)**

P value refers to comparison of each CKD Stage to the reference group (no CKD which is defined as estimated glomerular filtration rate ≥ 60ml/min/1.73m2).

*

P < .05.

**

P ≤ .0001.