Table 1.

Ciprofloxacin and novobiocin MICs of qnr-positive and qnr-negative strains with the quinolone resistance determinants found.

Strains	MIC (µg/ml)		PMQR	Topoisomerase mutationsa			Other PMQR	Reference
	Ciprofloxacin	Novobiocin		GyrA	ParC	ParE
6–42	0.125	40	qnrB1	WTb	WT	WT	-	[12]
EC35	0.25	80	qnrB6	WT	WT	WT	-	[11]
UAB4	0.5	40	qnrA1	WT	WT	WT	-	[9]
6–75	0.5	80	qnrB19	WT	WT	WT	-	[12]
3–41	0.5	80	qnrB4	S83L	WT	WT	-	[12]
3–48	1	80	qnrS1	WT	WT	WT	-	[12]
6–74	2	80	qnrS1	S83L	WT	WT	-	[12]
4	128	160	qnrA1	S83L, D87N	S80I	WT	aac(6’)-Ib-cr	[10]
29	128	160	qnrA1	S83L, D87N	S80I	WT	aac(6’)-Ib-cr	[10]
7	256	80	qnrA1	S83L, D87N	S80I, E84G	WT	-	[10]
10	256	320	qnrA1	S83L, D87N	S80I	WT	aac(6’)-Ib-cr	[10]
12	128	320	qnrA1	S83L, D87N	S80I	WT	aac(6’)-Ib-cr	[10]
76	1024	40	qnrA1	S83L, D87N	S80I	S458A	aac(6’)-Ib-cr, qepA1, oqxAB	[10]
3–62	0.016	320	-	WT	WT	WT	-	[12]
6–66	0.016	40	-	WT	WT	WT	-	[12]
3–25	0.03	80	-	WT	WT	WT	-	[12]
3–7	0.06	80	-	WT	WT	WT	-	[12]
3–33	0.06	80	-	WT	WT	WT	-	[12]
6–52	0.25	80	-	S83L	WT	WT	-	[12]
4–76	0.5	80	-	S83L	WT	WT	-	[12]
5–58	0.5	80	-	S83L	E84G	WT	-	[12]
5–66	1	80	-	S83L	S80I	WT	-	[12]
5–65	4	40	-	S83L	S80I	WT	-	[12]
5–81	32	80	-	S83L, D87N	S80I	WT	-	[12]
6–13	64	160	-	S83L, D87N	S80I	S458A	oqxAB	[12]
5–33	64	160	-	S83L, D87N	S80I	D420N	-	[12]
5–59	256	160	-	S83L, D87N	S80I	S458T	qepA1	[12]

^aMutations in gyrB were not detected.

^bWild type.