Table 1.
Correlations between islet preparation characteristics or donor attributes and insulin secretion in isolated human islets
| Baseline | First G15 | Whole G15 | First Tolb | Whole Tolb | Forskolin | SI First G15 | SI Whole G15 | |
|---|---|---|---|---|---|---|---|---|
| Islet purity |
−0.133 0.396 |
−0.169 0.279 |
−0.176 0.260 |
−0.257 0.096 |
−0.281 0.068 |
−0.184 0.243 |
−0.011 0.901 |
−0.049 0.802 |
| Islet size index |
0.398 0.008 |
0.433 0.004 |
0.498 0.001 |
0.451 0.002 |
0.438 0.003 |
0.454 0.003 |
0.069 0.661 |
0.107 0.494 |
| Cold ischemia time |
0.380 0.013 |
0.030 0.850 |
0.114 0.473 |
0.272 0.082 |
0.263 0.092 |
0.251 0.109 |
−0.220 0.162 |
−0.170 0.281 |
| Donor age |
−0.115 0.465 |
−0.281 0.069 |
−0.218 0.160 |
−0.301 0.050 |
−0.311 0.042 |
−0.248 0.114 |
−0.151 0.332 |
−0.070 0.656 |
| Donor BMI |
0.190 0.222 |
0.380 0.012 |
0.432 0.004 |
0.334 0.028 |
0.337 0.027 |
0.389 0.011 |
0.228 0.142 |
0.280 0.069 |
Correlation coefficients R were calculated by the test of Spearman and are presented with P value in italics.
Bold characters are used to highlight P values (0.05 or lower) indicating statistical significance of the correlation coefficient.
The six periods over which insulin secretion rates were averaged are defined in Figure 1.
SI, Stimulation Index was calculated for the first phase and the whole response to G15.