Table 1.

Studies reporting standardized mortality ratios in patients with non-functioning pituitary adenoma (those reviewing a subgroup of a previously studied population are not included)

Study	Country period covered	Number of patients	Surgery/radiotherapy	Follow-up (years) (range)	Standardized mortality ratio (95% CI)
Ntali et al. [8]	UK 1963–2011	546	100%/29%	Median 8.0 (1 month–48.5)	3.6 (2.9–4.5)
Nielsen et al. [11]	Denmark 1985–1996	192	100%/22%	Median 13.1 (8.0–20.0) (surviving subjects) 4.6 (0–18.6) (deceased subjects)	1.21 (0.93–1.59)
Tomlinson et al. [14]	UK 1992–2000	573 (all had hypopituitarism)	90%/42%	Not reported for patients with NFA	1.70 (1.34–2.15)
Olsson et al. [15]	Sweden 1987–2011	2795	Patients diagnosed before 1997 (12%) Treatment not available Patients diagnosed after 1997 (88%) 52%/4%	Mean 7 (0–25)	1.10 (1.00-1.20)