Table 4.

Cumulative incidence of major events after the index stroke or TIA

	TIA % (95% CI)	Non-fatal stroke % (95% CI)	Non-fatal AMI % (95% CI)	CV mortality % (95% CI)	Composite CV outcomea % (95% CI)	Non-fatal venous thrombosis % (95% CI)	Overall mortality % (95% CI)
Index TIA
30-day	0.37 (0.05–2.61)	–	–	0.37 (0.05–2.60)	0.74 (0.19–2.93)	–	0.37 (0.05–2.60)
90-day	1.49 (0.56–3.92)	–	–	0.37 (0.05–2.60)	1.86 (0.78–4.40)	–	0.37 (0.05–2.60)
6-month	1.87 (0.78–4.44)	–	–	0.75 (0.19–2.96)	2.61 (1.25–5.40)	–	1.13 (0.37–3.46)
12-month	3.48 (1.82–6.58)	–	–	0.75 (0.19–2.96)	4.21 (2.35–7.47)	0.79(0.20–3.12)	1.92 (0.80–4.56)
24-month	6.57 (4.07–10.5)	–	2.65 (1.20–5.80)	1.65 (0.62–4.35)	10.80 (7.47–15.5)	1.24 (0.40–3.80)	5.38 (3.15–9.09)
60-month	12.0 (8.26–17.2)	1.24 (0.31–4.95)	3.74 (1.88–7.40)	2.14 (0.89–5.08)	18.9 (14.2–24.9)	3.68 (1.74–7.73)	10.0 (6.69–14.9)
Index stroke
30-day	–	0.31 (0.04–2.20)	0.32 (0.04–2.23)	1.55 (0.65–3.68)	2.17 (1.04–4.50)	0.63 (0.16–2.51)	1.55 (0.65–3.68)
90-day	–	0.96 (0.31–2.95)	0.32 (0.04–2.23)	2.18 (1.04–4.51)	3.44 (1.92–6.12)	1.61 (0.67–3.83)	2.18 (1.04–4.51)
6-month	0.67 (0.17–2.65)	0.96 (0.31–2.95)	0.32 (0.04–2.23)	2.50 (1.26–4.94)	4.41 (2.64–7.34)	1.94 (0.88–4.27)	2.50 (1.26–4.94)
12-month	2.04 (0.92–4.49)	2.03 (0.92–4.47)	0.67 (0.17–2.64)	2.50 (1.26–4.94)	7.14 (4.75–10.6)	1.94 (0.88–4.27)	2.84 (1.49–5.40)
24-month	2.86 (1.44–5.66)	3.61 (1.96–6.63)	0.67 (0.17–2.64)	3.64 (2.02–6.49)	10.2 (7.23–14.3)	2.76 (1.38–5.46)	6.67 (4.29–10.3)
60-month	5.81 (3.32–10.1)	6.52 (3.90–10.8)	1.80 (0.65–4.91)	7.18 (4.52–11.3)	19.2 (14.6–25.0)	4.60 (2.46–8.49)	20.4 (15.4–26.6)

TIA transient ischemic attack, AMI acute myocardial infarction, CV cardiovascular

^aComposite CV outcome includes non fatal TIA, Stroke, AMI, and CV deaths, whichever occurs first