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. 2018 Mar 13;8:4454. doi: 10.1038/s41598-018-22730-x

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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A comparison between the three different groups (anodal, cathodal and sham) after stimulation revealed different significant effects. The comparison between cathodal and sham stimulation showed a significant difference for the theta frequency band (F = 2.83, p < 0.05) (see Fig. 7). This analysis showed increased activity overlaying the rostral anterior cingulate cortex extending into the pregenual anterior cingulate cortex, ventromedial prefrontal cortex, and orbitofrontal cortex and to a smaller extend to the posterior cingulate cortex after cathodal stimulation in comparison to sham stimulation. No significant effect was obtained for the delta, alpha1, alpha2, beta1, beta2, beta3, and gamma frequency band.