Table 4.
The association between maternal urinary triclosan levels and birthweight in female and male infants.
| Mean ± SD | Infant birthweight (g) |
||
|---|---|---|---|
| Unadjusted β (95% CI) | Adjusted β (95% CI)d | ||
| Female | |||
| Urinary TCS (ng/mL) | |||
| Low (n = 92) | 3300 ± 422 | Ref. | Ref. |
| Medium (n = 109) | 3398 ± 390 | 97.9 (−12.9, 208.7)a | 41.9 (−64.8148.5) |
| High (n = 97) | 3471 ± 393 | 170.2 (56.3, 284.1)c | 122.8 (13.9231.6)b |
| Trend test | ptrend = .003 | ptrend = .03 | |
| Linear log (TCS) | 50.9 (18.8, 83.0)c | 37.2 (6.9, 67.5)b | |
| Male | |||
| Urinary TCS (ng/mL) | |||
| Low (n = 114) | 3507 ± 372 | Ref. | Ref. |
| Medium (n = 98) | 3464 ± 409 | −43.2 (−151.5, 65.1) | −88.7 (−190.6, 13.3)a |
| High (n = 110) | 3521 ± 428 | 13.4 (−91.7, 118.4) | −2.0 (−98.5, 94.6) |
| Trend test | ptrend = .81 | ptrend = .99 | |
| Linear log (TCS) | 6.1 (−22.2, 34.3) | 0.03 (−26.0, 26.1) | |
| p for effect modificatione | .04 | .05 | |
a
p < .1.
b
p < .05.
c
p < .01.
d
Covariates included: log (creatinine), maternal age, height, prepregnancy BMI categories, GDM, education, passive smoking, parity and gestational age.
e
p value for effect modification estimated in the models with sex (male, female), log (TCS) (linear term) and interaction of the two.