Skip to main content
. 2018 Feb 12;20(3):244–255. doi: 10.1016/j.neo.2018.01.004

Figure 6.

Figure 6

Plk2 gene body methylation and mRNA expression remain unaltered in colorectal cancer as compared to normal: TCGA. Plk2 Gene methylation normal versus colorectal tumors: A) 5′UTR to the First Exon (P=0.2), B) Transcription Start Site (TSS)(P=0.9), C) Gene Body (P<0.001, and D) Plk2 mRNA expression (RSEM values) in normal versus colorectal tumors (P=0.003). Panels A-C: RNA seq by expectation-maximization (RSEM). Beta-values above 0.4 were considered methylated. Cancer Genome Atlas (TCGA) search yielded 312 colorectal cancers with methylation data of which 305 cases also had mRNA data.