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. 2018 Jan 31;11:1–8. doi: 10.1016/j.omtn.2018.01.003

Table 1.

Logistic Regression Analyses on Associations between Selected Polymorphisms and Neuroblastoma Risk in Chinese Children

miRNA SNP Allele
Case (n = 393)
Control (n = 812)
Heterozygous (AB versus AA)
Dominant (AB/BB versus AA)
Recessive (BB versus AB/AA)
HWE
A B AA AB BB AA AB BB AOR (95% CI)a p Valuea AOR (95% CI)a p Valuea AOR (95% CI)a p Valuea
miR-27a rs895819 T C 220 153 20 442 312 58 0.99 (0.77–1.27) 0.913 0.94 (0.74–1.20) 0.623 0.70 (0.42–1.18) 0.184 0.772
miR-34b/c rs4938723 T C 221 107 49 377 358 75 0.51 (0.39–0.67)b <0.0001b 0.62 (0.48–0.79)b 0.0001b 1.46 (1.00–2.15) 0.052 0.448
miR-137 rs1625579 T G 343 46 3 719 90 1 1.07 (0.74–1.57) 0.717 1.13 (0.78–1.64) 0.519 6.23 (0.65–60.00) 0.114 0.290
miR-146a rs2910164 C G 142 189 60 282 397 130 0.94 (0.72–1.23) 0.671 0.94 (0.73–1.20) 0.607 0.94 (0.68–1.32) 0.728 0.621
miR-149 rs2292832 T C 286 62 32 560 172 59 0.70 (0.51–0.97)b 0.032b 0.79 (0.60–1.05) 0.106 1.14 (0.73–1.79) 0.559 <0.001
miR-196a2 rs11614913 T C 107 192 94 230 399 183 1.04 (0.78–1.39) 0.793 1.06 (0.81–1.39) 0.673 1.08 (0.81–1.43) 0.607 0.691
miR-218 rs11134527 A G 154 164 73 276 403 131 0.73 (0.56–0.96)b 0.022b 0.80 (0.62–1.02) 0.073 1.19 (0.86–1.63) 0.290 0.425
miR-423 rs6505162 C A 244 132 17 522 258 31 1.09 (0.84–1.42) 0.497 1.10 (0.86–1.41) 0.448 1.13 (0.62–2.07) 0.694 0.900
miR-608 rs4919510 G C 127 190 76 227 405 179 0.84 (0.64–1.11) 0.217 0.81 (0.63–1.06) 0.122 0.84 (0.62–1.14) 0.263 0.948

AOR, adjusted odds ratio; CI, confidence interval; HWE, Hardy-Weinberg equilibrium.

a

Adjusted for age and gender.

b

For these values, the 95% CI excluded 1 or p < 0.05.