Table 3.

Results of False-Positive Report Probability Analysis for Significant Findings

Genotype and Variables	OR (95% CI)	p Valuea	Statistical Powerb	Prior Probability
				0.25	0.1	0.01	0.001	0.0001
rs4938723 T > C
TC versus TT	0.51 (0.39–0.67)	<0.0001	0.039	0.000c	0.000c	0.003c	0.033c	0.254
TC/CC versus TT	0.62 (0.48–0.79)	0.0001	0.243	0.001c	0.004c	0.039c	0.291	0.805
C versus T	0.82 (0.68–0.99)	0.039	0.976	0.108c	0.266	0.799	0.976	0.998
TC/CC versus TT
≤18 months old	0.55 (0.36–0.85)	0.007	0.194	0.096c	0.242	0.779	0.973	0.997
>18 months old	0.64 (0.47–0.87)	0.004	0.392	0.030c	0.084c	0.503	0.911	0.990
Females	0.52 (0.35–0.76)	0.001	0.096	0.021c	0.062c	0.420	0.880	0.987
Males	0.70 (0.51–0.97)	0.032	0.607	0.136c	0.320	0.838	0.981	0.998
Adrenal gland as site of origin	0.44 (0.31–0.63)	<0.0001	0.015	0.002c	0.006c	0.062c	0.399	0.869
I + II + 4 s	0.63 (0.44–0.88)	0.008	0.351	0.060c	0.161c	0.679	0.955	0.995
III + IV	0.61 (0.44–0.83)	0.002	0.278	0.019c	0.055c	0.391	0.866	0.985
rs11134527 A > G
AG versus AA	0.73 (0.56–0.95)	0.021	0.820	0.071c	0.187c	0.717	0.962	0.996
Males	0.71 (0.51–0.99)	0.044	0.648	0.169c	0.378	0.870	0.985	0.999

OR, odds ratio; CI, confidence interval.

^aChi-square test was used to calculate the genotype frequency distributions.

^bStatistical power was calculated using the number of observations in each subgroup and the corresponding ORs and p values in this table.

^cThe level of false-positive report probability threshold was set at 0.2 and noteworthy findings are presented.