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. 2018 Feb 10;18:433–442. doi: 10.1016/j.nicl.2018.02.010

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© 2018 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Fig. 4 — MDS-UPDRS Part III vs. [¹⁸F]-fallypride binding potential. Scatterplots of BP_ND (y-axis) vs. scores on the MDS-UPDRS Part III off-medication (x-axis) fit with a linear regression for the PD group. Age, sex, ROI volume, disease duration, and LEDD were included as covariates in this analysis. A significant positive correlation between BP_ND and MDS-UPDRS Part III score was observed for the (A) putamen and (B) globus pallidus. No significant correlations were observed between BP_ND and MDS-UPDRS Part II for any ROI. This indicates that there is a positive relationship between D_2/3 expression in the putamen and globus pallidus, and severity of PD motor symptoms.