Table 3.

Cox regression analysis

Variable	p	HR	95% CI
Univariate cox regression analysis
ECOG	0.003
AGE ≥ 65	0.02	0.49	0.26–0.92
LDH baseline ≥ 300 U/L	0.008	0.41	0.2–0.7
Bortezomib-based regimens (first line)	0.03	0.46	0.22–0.9
Bortezomib-based regimens + ASCT (first line)	0.01	0.38	0.2–0.8
ASCT	0.01	0.40	0.2–0.8
≥VGPR	0.009	0.40	0.20–0.8
Multivariate cox regression analysis
LDH baseline ≥ 300 U/L	0.03	0.45	0.2–0.9
≥VGPR	0.01	0.39	0.2–0.8

ECOG Eastern Cooperative Oncology Group, LDH lactate dehydrogenase, vgPR very good partial response, ASCT autologous stem cell transplantation, HR hazard ratio