Table 1.
Characteristics of mcr-1-positive E. coli clinical isolates
| Center | Strain code | Date of isolation | Patient data (sex, age [years]) | Hospital service/per ward | Colistin MIC value (mg/L) | Other BL resistance determinants | ESBL profile | Sequence type | Rep-PCR profile | Inc-type | Phylogroup |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Busto A. | 01-EC01 | Oct. 2016 | M, 65 | Outpatient | 4 | – | Neg | ST354 | 1 | IncX4 | D |
| Lecco | 02-EC08 | Aug. 2016 | M, 52 | Rehabilitation | 8 | TEM-1 | Neg | ST617 | 6 | IncX4 | A |
| Lecco | 02-EC09 | Aug. 2016 | F, 87 | General surgery | 4 | TEM-1 | Neg | ST93 | 8 | IncHI2 | A |
| Lodi | 04-EC16 | Jun. 2016 | M, 83 | Outpatient | 4 | TEM-1, SHV-12 | Pos | ST88 | 2 | IncX4 | A |
| Lodi | 04-EC17 | Jun. 2016 | F, 83 | Outpatient | 8 | TEM-1 | Neg | ST428 | 3 | IncHI2 | B2 |
| Lodi | 04-EC18 | Jul. 2016 | F, 94 | Rehabilitation | 8 | TEM-1 | Neg | ST117 | 5 | IncHI2 | D |
| Lodi | 04-EC21 | Aug. 2016 | M, 74 | Outpatient | 4 | – | Neg | new ST | 7 | IncX4 | A |
| Lodi | 04-EC22 | Aug. 2016 | M, 77 | Outpatient | 8 | TEM-1 | Neg | ST359 | 9 | IncX4 | B1 |
| Vimercate | 06-EC05 | Jun. 2016 | F, 77 | Outpatient | 4 | SHV-12 | Pos | ST69 | 4 | IncX4 | D |
| Vimercate | 06-EC07 | Aug. 2016 | F, 73 | Outpatient | 8 | – | Neg | ST117 | 5 | IncX4 | D |
Abbreviations: BL, beta-lactam; ESBL, extended-spectrum beta-lactamase; F, female; M, male; Neg, negative; Pos, positive; Rep-PCR, repetitive sequence-based PCR; ST, sequence type; Aug, August; Jun, June; Oct, October.