Table 5.
Correlation Between High-Resolution Computed Tomographic Patterns and Lung Function (Indices of Airflow Limitation)
| HRCT abnormality | Association With Lung Function, Spearman Rank Correlation Coefficient, rs (P Value) | |||
|---|---|---|---|---|
| FEV1 | FVC | FEF25%–75% | FEV1/ FVC | |
| Bronchiectasis extent | −0.50 (<.001) | −0.36 (.002) | −0.44 (<.001) | −0.26 (.03) |
| Bronchiectasis severity | −0.49 (<.001) | −0.36 (.002) | −0.44 (<.001) | −0.26 (.03) |
| Bronchial wall thickening | −0.43 (<.001) | −0.34 (.003) | −0.34 (.003) | NS |
| Small-airway plugging | −0.40 (<.001) | −0.33 (.005) | −0.37 (.01) | NS |
| Large-airway plugging | −0.42 (<.001) | −0.38 (.001) | −0.36 (.002) | NS |
| Volume loss | −0.38 (.001) | −0.34 (.003) | NS | NS |
| Decreased attenuation | −0.52 (<.001) | −0.42 (<.001) | −0.42 (<.001) | NS |
Abbreviations: FEF25%–75%, forced expiratory flow, mid-expiratory phase; FEV1, forced expiratory volume in first second of expiration; FVC, forced vital capacity; NS, not significant.