Table 1.
Characteristics of Study Participants
| Acute GVHD | Total | ||||
|---|---|---|---|---|---|
| None | Grade 1–2 | Grade 3–4 | |||
| Number | 14 | 38 | 14 | 66 | |
| Age range, y (mean) | 38–71 (62) | 30–69 (50) | 22–73 (54) | ||
| Disease | Acute lymphoblastic leukemia (%) | 0 (0.0) | 3 (7.9) | 1 (7.1) | 4 (6.1) |
| Acute myeloid leukemia (%) | 3 (21.4) | 10 (26.3) | 4 (28.6) | 17 (25.8) | |
| Chronic lymphoblastic leukemia (%) | 1 (7.1) | 2 (5.3) | 1 (7.1) | 4 (6.0) | |
| Chronic myeloid leukemia (%) | 0 (0.0) | 1 (2.6) | 0 (0.0) | 1 (1.5) | |
| Hodgkin’s disease (%) | 0 (0.0) | 0 (0.0) | 2 (14.3) | 2 (3.0) | |
| Hemophagocytic lymphohistiocytosis (%) | 0 (0.0) | 1 (2.6) | 0 (0.0) | 1 (1.5) | |
| Myelodysplastic syndrome (%) | 6 (42.9) | 15 (39.5) | 3 (21.4) | 24 (36.4) | |
| Multiple myeloma (%) | 1 (7.1) | 1 (2.6) | 0 (0.0) | 2 (3.0) | |
| Non-Hodgkin’s lymphoma (%) | 3 (21.4) | 4 (10.5) | 3 (21.4) | 10 (15.2) | |
| Primary nasopharyngeal lymphoma (%) | 0 (0.0) | 1 (2.6) | 0 (0.0) | 1 (1.5) | |
| Transplant a | Related (%) | 7 (50.0) | 25 (65.8) | 8 (57.1) | 40 (60.6) |
| Mini (%) | 9 (64.3) | 6 (15.8) | 6 (42.9) | 21 (31.8) | |
| Matched (%) | 13 (92.9) | 35 (92.1) | 12 (85.7) | 60 (90.9) | |
| GVHD diagnosis day post transplant (mean) | 8–85 (39) | 16–61 (32.4) | |||
Abbreviation: GVHD, graft-versus-host disease.
aMini: nonmyeloablative conditioning.