Table 3.

Effect of Randomized Treatment on Mean Osteoprotegerin Levels at Discharge and at 1 and 6 Months After Randomization

Visit	Treatment	na	Mean (SD)	Geometric Meanb	Ratio of Geometric Means (95% CI)	P Valuec
Discharge	Ticagrelor	2263	2.62 (1.24)	2.39	1.01 (0.99–1.02)	0.5958
	Clopidogrel	2300	2.56 (1.15)	2.38
Month 1	Ticagrelor	2103	2.46 (0.98)	2.28	0.99 (0.97–1.01)	0.2507
	Clopidogrel	2134	2.43 (0.91)	2.30
Month 6	Ticagrelor	1513	2.46 (0.94)	2.30	1.01 (0.99–1.04)	0.1730
	Clopidogrel	1571	2.39 (0.91)	2.26

CI indicates confidence interval.

^an includes patients with osteoprotegerin samples available at both baseline and the respective visit.

^bThe geometric means are calculated using the antilogarithms of the model‐adjusted means of the logarithm‐transformed data.

^c P values from an ANCOVA model with the natural logarithm of osteoprotegerin as the outcome variable and logarithm baseline osteoprotegerin and randomized treatment (ticagrelor or clopidogrel) as independent variables.