Table 1.
Cohort Characteristics
| EXPT (n=176) | CTRL (n=134) | P Value | |
|---|---|---|---|
| Maternal data | |||
| Age, y, mean (range) | 31.4 (18–46) | 31.8 (21–43) | 0.47 |
| Family history of CVD | 128 (74) | 102 (77) | 0.65 |
| University education | 82 (47) | 84 (63) | 0.004 |
| Pregnancy data | |||
| Maternal smoking | 9 (5) | 2 (1) | 0.09 |
| Preeclampsia | 16 (10) | 0 | NA |
| Multiple birth | 29 (17) | 0 | NA |
| Neonatal data | |||
| Gestational age, wk, mean (SD); range | 24.9 (1.0); 22–26 | 39.4 (1.2); 37–41 | NA |
| Boys | 98 (55) | 79 (60) | 0.53 |
| Birth weight, g, mean (SD); range | 788 (169); 348–1161 | 3591 (461); 2430–4315 | NA |
| SGA at birth | 27 (16) | 0 | NA |
| SGA at 36 wk of postmenstrual age | 76/161 (47) | – | NA |
| PDA | 104 (61) | 0 | NA |
| 6.5‐y follow‐up, mean (SD) | |||
| Age, mo | 80.8 (2.3) | 81.1 (2.0) | 0.23 |
| Weight, kg | 20.6 (3.6) | 24.3 (3.9) | <0.001 |
| Height, cm | 118.1 (5.6) | 123.1 (5.0) | <0.001 |
| BMI, kg/m2 | 14.7 (1.6) | 16.0 (2.0) | <0.001 |
| BSA, m2 | 0.82 (0.09) | 0.91 (0.09) | <0.001 |
| HR, beats/min | 88 (13) | 85 (9) | 0.016 |
| SBP, mm Hg | 98 (8) | 97 (8) | 0.38 |
| DBP, mm Hg | 57 (6) | 55 (6) | 0.005 |
Data are n (%) if not indicated otherwise. BMI, body mass index; BSA, body surface area; CTRL, control (born at term); CVD, cardiovascular disease; DBP, diastolic blood pressure; EXPT, extremely preterm; HR, heart rate; PDA, patent ductus arteriosus; SBP, systolic blood pressure; SGA, small for gestational age.